Alpha power oscillation in the frontal cortex under Bromazepam and Modafinil effects

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Alpha power oscillation in the frontal cortex under Bromazepam and Modafinil effects.

OBJECTIVE Our aim was to investigate and compare the neuromodulatory effects of bromazepam (6 mg) and modafinil (200 mg) during a sensorimotor task analyzing the changes produced in the absolute alpha power. METHOD The sample was composed of 15 healthy individuals exposed to three experimental conditions: placebo, modafinil and bromazepam. EEG data were recorded before, during and after the e...

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Uncontrolled stress produces severe defect in development of frontal cortex in the rat

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Uncontrolled stress produces severe defect in development of frontal cortex in the rat

One of the most important factors in drug addiction is stress. It has been shown that animals with prenatal stress history are more risky for drug dependence. It have also been shown that frontal cortex play a role in drug dependence. In the present study the effects of two kinds of mild stress during pregnancy on the development of frontal cortex in Wistar rats (250-300 g) were investigated. F...

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ژورنال

عنوان ژورنال: Arquivos de Neuro-Psiquiatria

سال: 2015

ISSN: 0004-282X

DOI: 10.1590/0004-282x20150140